Ceylon Journal of Medical Science
Permanent URI for this collectionhttps://dl.nsf.gov.lk/handle/1/6841
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Item Effects of different Zinc levels in the sperm culture medium on sperm recovery and quality of sperms in the swim up procedure for sperm processing(University of Colombo. Colombo, 2006) Dissanayake, D.M.A.B.; Wijesinghe, P.S.; Ratnasooriya, W.D.; Wimalasena, S.; Palihawadana, T.S.Item Reproductive hormones in seminal plasma; it's effect on semen quality(University of Colombo. Colombo, 2005) Wijeratna, S.; Seneviratna, H.R.; Ratnasooriya, W.D.Item Gastroprotective activity of hot ethanolic extract of Alpinia Calcarata rhizome in rats(University of Colombo. Colombo, 2005) Arambewela, L.S.R.; Arawwawala, L.D.A.M.; Ratnasooriya, W.D.Item Effect of oxytocin on fertility of male rats(University of Colombo. Colombo, 2004) Ratnasooriya, W.D.; Jayakody, J.R.A.C.; Dharmasiri, M.G.It is now recognised that oxytocin (OT) modulates several aspects of male reproduction. However, its overall impact on male fertility remains unknown. Thus, the aim of this study was to examine the effect of OT om male fertility. This was investigated in rats using three doses [0.1 international units (IU) of OT once a day (n=9) twice a day and thrice a day , given intrapertioneally for 7 consecutive days] and a non competitive serial mating trial (on days 1,3 and 7 of treatment and day 7 post treatment). The OT caused marked oligozoospermia without provoking toxic side effects (in terms of teratozoospermia, overt signs of toxicity, renotoxicity , hepatotoxicity or haemotoxicity) or compromising libido, mating peroformance and fertility (in terms of quantal pregnance, number of uterine implants and indices of implantation and fertility), The oligozoospermia was mediated by retrograde ejaculation and by impairment of ejaculatory contraction of vas (as judged by inhibition of elctrically elicited contraction of isolated vas) and probably epididymis. It is possible that OT analogues may be developed as post-testicular male contraceptives.Item Antigestational effects of Icon. a pyrethroid insecticide on mid pregnancy of rats(University of Colombo. Colombo, 2004) Ratnasooriya, W.D.; Ratnayake, S.S.K.; Jayatunge, Y.N.A.Item Effects of some non steroidal anti-inflammatory drugs on rat sperm hyperactivation in vitro(University of Colombo. Colombo, 2003) Ratnasooriya, W.D.; Hapuarachchi, C.T.; Jayakody, J.R.A.C.Item Effects of different Zinc levels in the sperm culture medium on sperm recovery and quality of sperms in the swim up procedure for sperm processing(University of Colombo. Colombo, 2006) Dissanayake, D.M.A.B.; Wijesinghe, P.S.; Ratnasooriya, W.D.; Wimalasena, S.; Palihawadana, T.S.