Ceylon Journal of Medical Science
Permanent URI for this collectionhttps://dl.nsf.gov.lk/handle/1/6841
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Item Effects of different Zinc levels in the sperm culture medium on sperm recovery and quality of sperms in the swim up procedure for sperm processing(University of Colombo. Colombo, 2006) Dissanayake, D.M.A.B.; Wijesinghe, P.S.; Ratnasooriya, W.D.; Wimalasena, S.; Palihawadana, T.S.Item Ultrastructure of endothelial cells of fetal capillaries of placentae of women with pregnancy induced hypertension(University of Colombo. Colombo, 2006) Salgado, S.S.; Angunawela, P.; De Tissera, A.; Sirisena, J.Item Suitability of selection criteria as a measure of outcome of medical graduates. University of Colombo(University of Colombo. Colombo, 2006) Mettananda, D.S.G.; Wickramasinghe, V.P.; Kudolugoda Arachchi, J.; Lamabadusuriya, S.P.; Ajanthan, R,; Kottahachchi, D.Item Reproductive hormones in seminal plasma; it's effect on semen quality(University of Colombo. Colombo, 2005) Wijeratna, S.; Seneviratna, H.R.; Ratnasooriya, W.D.Item Effect of oxytocin on fertility of male rats(University of Colombo. Colombo, 2004) Ratnasooriya, W.D.; Jayakody, J.R.A.C.; Dharmasiri, M.G.It is now recognised that oxytocin (OT) modulates several aspects of male reproduction. However, its overall impact on male fertility remains unknown. Thus, the aim of this study was to examine the effect of OT om male fertility. This was investigated in rats using three doses [0.1 international units (IU) of OT once a day (n=9) twice a day and thrice a day , given intrapertioneally for 7 consecutive days] and a non competitive serial mating trial (on days 1,3 and 7 of treatment and day 7 post treatment). The OT caused marked oligozoospermia without provoking toxic side effects (in terms of teratozoospermia, overt signs of toxicity, renotoxicity , hepatotoxicity or haemotoxicity) or compromising libido, mating peroformance and fertility (in terms of quantal pregnance, number of uterine implants and indices of implantation and fertility), The oligozoospermia was mediated by retrograde ejaculation and by impairment of ejaculatory contraction of vas (as judged by inhibition of elctrically elicited contraction of isolated vas) and probably epididymis. It is possible that OT analogues may be developed as post-testicular male contraceptives.Item A prototype medical decision support system that utilizes 'sensitivity' and 'specificity' of a clinical feature for diagnosis. a novel approach(2004) Senaviratne, G.M.M.M.A.; Nanayakkara, N.K.P.K.; Walgama, K.; Yatawatte, A.B.; Goonasekera, C.D.A.A prototype computer based secision support system was developed to simulate a doctors' decision making process using a relational database consisting 25 clinical features and 10 common diseases encountered in critical care. The relationship between diseases and clinical features was cited by a sensitivity and a specificity value for each clinical expert arbitrarily determined the sensitivity and specificity values. The cumulative probability values of each disease in relation to presenting clinical features were calculated using simple decision algorithm with ranked values to determine the most probable diagnosis. THe database was built using microsoft Access and the interfaced in Visual Basic environment. IN the program the output window provides the user with 5 most likely diagnoses with a display of ranked probability values. This differential diagnosis can be refined repetitively using new information. THe system was validated using data from 26 patients admitted to a regional intensive care unit. The prototype decision support system was able to predict the true diagnosis with a sensitivity value of 88% as rank 1 an 96% as both rank 1 or 2. Thus results show that this novel approach of decision support could be more reliable t assist a doctor.Item Variation in blood pressure with age and sex of the Uva-Bintenne Veddas(University of Colombo. Colombo, 2004) Wikramanayake, E.R.; Chandrasekera, M.S.The blood pressure of 496(227 males and 269 females) Uva -Bintenne veddas in the age range 1 to 80 years were recorded at Hennanigal South and Dambana. In both males and females there is no progressive increase of pressure with age. In the females both curves are more variable with the systolic pressure higher than in the males except in the age range 31-40 and the diastolic pressure higher up to 50 years. When compared with a 1989 study of a rural breeding isolate of the sinhalese the pressures of both males and females were significantly higher in the age range 1-15 years with no steep rise of the curve from 1-18 years. The aetiology of the difference is postulated to be genetic rather than environmental.Item Effect of ambient temperature on recovery from muscular exercise(University of Colombo. Colombo, 2004) Amarasena, J.; Rajaratne, A.A.J.; Balasuriya, P.; Amarasena, N.Item Antigestational effects of Icon. a pyrethroid insecticide on mid pregnancy of rats(University of Colombo. Colombo, 2004) Ratnasooriya, W.D.; Ratnayake, S.S.K.; Jayatunge, Y.N.A.Item The prevalence and mode of inheritance of Carabelli trait in the Sinhalese(University of Colombo. Colombo, 2004) Dissanayake, U.; Chandrasekera, M.S.; Wikramanayake, E.R.